Drug Development BMS to buy MyoKardia for access to late-stage heart disease drug The $13 billion deal bolsters the big pharma firm’s cardiovascular disease pipeline by Lisa M. Jarvis

SOUTH SAN FRANCISCO, Calif., May 02, 2016 -- MyoKardia, Inc. , a clinical stage biopharmaceutical company pioneering a precision medicine approach for the treatment of heritable cardiovascular | …

Bristol-Myers Squibb (BMS) has agreed to acquire MyoKardia for $13.1 billion cash, in a deal designed to expand the buyer’s cardiovascular drug portfolio with a potential blockbuster for a form 2020-10-05 · MyoKardia recently completed a Phase 2 study of its mavacamten drug, which targets patients with hypertrophic cardiomyopathy, a progressive heart disease that increases the risk of strokes, heart 2017-08-07 · MyoKardia drug improves blood flow in patients with serious, inherited form of heart disease. By Adam Feuerstein Aug. 7, 2017. Reprints. Yoshito Laboratory, Cira, Kyoto University. MyoKardia | 12,210 followers on LinkedIn.

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2020-10-05 · “The lead asset for MyoKardia is mavacamten,” which is a “potentially revolutionary medicine for the treatment of the very serious disease of obstructive HCM.” Obstructive HCM, or hypertrophic 2020-05-11 · A n experimental drug to treat an inherited, progressive heart disease clearly improved the symptoms of patients, its maker, MyoKardia, said Monday. The full data have not yet been published or MyoKardia expects to submit marketing application to the U.S. health regulator for obstructive HCM in the first quarter of 2021 after the drug met the main goal of a late-stage study. The company 2020-10-05 · The MyoKardia drug is a small molecule designed to block the way that myosin and another protein, actin, interact in the process of muscle contraction. The drug’s effect is targeted to the heart BMS acquires MyoKardia, maker of drugs for cardiovascular disease, for $13.1B The companies expect the deal to close in the fourth quarter. MyoKardia's lead drug candidate is mavacamten, which it MyoKardia’s lead pipeline drug, code-named mavacamten, treats a chronic heart condition that can cause irregular heart rhythms in some patients and even death. Bristol plans to ask U.S. health MyoKardia will regain full rights to its drug programmes when the deal ends in April, including the experimental drugs mavacamten and MYK-491.

MyoKardia recently announced a new clinical trial of its drug, mavacamten (formerly known as MYK-461) which will compare the clinical results of mavacamten with septal reduction therapies currently used in clinical practice, i.e. the open heart surgical procedure known as septal myectomy and the catheter based procedure known as alcohol septal ablation.

Driven by the heart | Our Mission: Change the world for people with cardiovascular disease through bold and innovative science. MyoKardia is a clinical MyoKardia (NASDAQ:MYOK) +1.3% premarket, has announced a license agreement with LianBio, for the development and commercialization of its lead drug candidate, mavacamten for hypertrophic More importantly, reduction or complete elimination in obstruction of the left ventricle was observed with the drug treatment.

MyoKardia finished a successful Phase 3 trial of its investigational drug mavacamten for a heart disease called hypertrophic cardiomyopathy. Citigroup Global Markets analyst Mohit Bansal thinks

The deal is expected to close before the end of 2020.

By Adam Feuerstein Aug. 7, 2017.
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MyoKardia is a clinical MyoKardia (NASDAQ:MYOK) +1.3% premarket, has announced a license agreement with LianBio, for the development and commercialization of its lead drug candidate, mavacamten for hypertrophic More importantly, reduction or complete elimination in obstruction of the left ventricle was observed with the drug treatment. Although the company hasn’t revealed the data, it will form the basis of New Drug Application that MyoKardia plans to file with the USFDA in the first quarter of 2021.

The drug’s effect is targeted to the heart and does not affect any other types of muscle in the body.
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Bristol Myers Squibb on Monday said it will pay $13.1 billion to acquire MyoKardia, a developer of medicines for genetic forms of heart disease. Bristol Myers is paying $225 per share for MyoKardia, a roughly 61% premium to the biotech's $139.60 closing price on Friday. The acquisition gives the larger drugmaker rights to mavacamten, a treatment for a chronic heart condition known as obstructive hypertrophic cardiomyopathy that could be headed for a regulatory review by next year.

MyoKardia drug boosts blood flow for patients with inherited Dysfunktion i hjärtkammarens hjärtkammare: orsaker, symtom Foto 18. Okontrollerad angiogen  New Drugs for the Treatment of Migraine The newest drugs for the acute Myokardia presenterade fas 3-data och Biohaven lanserade ny  vs Antiaryhythmic Drug Therapy for Atrial Fibrillation (CABANA) -studien, i en Albert avslöjar att han erhöll ersättning från Myokardia och forskningsbidrag  Resultaten publicerades samtidigt i New England Journal of Medicine. Intarcia, Merck, MyoKardia, Pfizer, Sanofi, Vertex, Zeus, Cubist och Quest Diagnostics. med ett annat läkemedel - från US Food and Drug Administration (FDA). Förutom Bristol Myers Squibb stänger 13,1 miljarder dollar förvärv av MyoKardia.